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1 - 8 of 8 results
The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.
Comparative analysis using LC-QTOF/MS between innovator and biosimilar of Rituximab
Reversed-phase LC primary structure characterization workflow using Agilent AdvanceBio RP-mAb columns and Agilent 1260 Infinity Bio-Inert LC system
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
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The AdvanceBio Peptide Mapping column gives 100% rhEPO sequence coverage with 45 glycopeptide matches.
| Publication Part Number | 5991-1813EN | |||
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Reduce peptide mapping time without losing resolution with Agilent AdvanceBio Peptide Mapping BioHPLC columns.