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Demonstion of the use of multiple heart-cutting two-dimensional liquid chromatography for automated desalting of glucagon from an MS incompatible USP method.
The Agilent AdvanceBio SEC column together with the Agilent 1260 Infinity II Bio-inert System is an ideal combination for the aggregate analysis of ADCs
The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
Presents a method for the rapid analysis of a monoclonal antibody using the Agilent AdvanceBio SEC 200 ? 19 μm column.
Comparison of HPLC method and a quick method developed using the Cary 60 UV-Vis
This application note describes a robust LC/MS method for the analysis of native protein analysis.
Agilent-NIST mAb application compendium
The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products.
A method using the Agilent AdvanceBio Gly-X 2-AB Express kit and 2-AB labeling for the release of glycans with LC/FLD analysis.
Presents the use of the AdvanceBio HIC column to resolve monoclonal antibody variants from their native form without mAb digestion into subunits.
Presents a method for peptide mapping using an Agilent LC/MSD XT and 1290 Infinity II LC.
Size Exclusion Chromatography Method Development of NIST mAb Using an Agilent AdvanceBio SEC 200 ?, 1.9 μm Column
Describes a comparison between the Agilent AdvanceBio SEC 200 ? 1.9 μm column and other vendors' SEC columns in terms of mAb and ADC analysis.
This app note presents a complete high-throughput workflow solution to analyze a variety of mAb products.
Describes the use of the new AdvanceBio HIC column, with method optimization, to assess DAR values of ADCs.
An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements
This application note demonstrates three approaches to quantitatively understand the glycosylation present for a given mAb.
Size exclusion chromatography with light scattering detection was used to investigate the impact of varying SDS concentration on protein molecules.
This application note demonstrates how to increase sample throughput for glycan characterization workflows using the Agilent biopharmaceutical solution.
This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.