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Presents the use of the AdvanceBio HIC column to resolve monoclonal antibody variants from their native form without mAb digestion into subunits.
- Publication Part Number: 5994-0199EN
- Created: 10 July 2019
- 628 KB
This app note presents a complete high-throughput workflow solution to analyze a variety of mAb products.
- Publication Part Number: 5991-7813EN
- Created: 19 Nov 2018
- 1 MB
Presents the use of AdvanceBio Desalting-RP cartridges to pretreat mAb and ADC samples before MS analysis.
- Publication Part Number: 5994-0302EN
- Created: 01 Nov 2018
- 2 MB
Describes the use of the new AdvanceBio HIC column, with method optimization, to assess DAR values of ADCs.
- Publication Part Number: 5994-0149EN
- Created: 31 July 2018
- 831 KB
An Integrated Workflow for Intact and Subunits of Monoclonal Antibody Accurate Mass Measurements
- Publication Part Number: 5991-8445EN
- Created: 29 Mar 2018
- 14 MB
This application describes an LC method for a quick and high sensitivity method for the quantitative analysis of amino acids using an Agilent AdvanceBio AAA column.
- Publication Part Number: 5991-6572EN
- Created: 25 Sep 2017
- 883 KB
This app note presents a complete high-throughput workflow solution for sequence mapping analysis.
- Publication Part Number: 5991-7815EN
- Created: 23 Feb 2017
- 2 MB
This app note presents a high-throughput workflow that enables simultaneous, highly reproducible sample digestion and cleanup.
- Publication Part Number: 5991-7811EN
- Created: 15 Feb 2017
- 2 MB
An aggregate analysis workflow for SEC mobile phase optimization and characterization of mAb aggregation profiles
- Publication Part Number: 5991-7476EN
- Created: 04 Nov 2016
- 544 KB
Agilent PLRP-S column demonstrates superior separation performance for the analysis of mAbs and ADC at both intact and fragment levels
- Publication Part Number: 5991-7163EN
- Created: 01 Aug 2016
- 288 KB
Agilent AdvanceBioSEC columns used for fast, high resolution, sensitive, and reproducible separation and quantitation of mAbs and Antibody Drug Conjugate,
- Publication Part Number: 5991-7165EN
- Created: 01 Aug 2016
- 905 KB
Online 2D-LC characterization of monoclonal antibodies using SEC in the first dimension and IEX in the second dimension
- Publication Part Number: 5991-6906EN
- Created: 01 June 2016
- 538 KB
"Agilent AdvanceBio SEC columns have been developed to provide optimum performance regardless of the instrument used.
- Publication Part Number: 5991-6302EN
- Created: 01 Jan 2016
- 1 MB
Agilent AdvanceBio SEC columns perform better in resolution, sensitivity, peak capacity and shape of mAbs and ADCs using low pressure LC and aqueous mobile phase.
- Publication Part Number: 5991-6474EN
- Created: 01 Dec 2015
- 527 KB
Agilent Bio Mab WCX separates charged variants of papain-digest monoclonal antibody, following by MS characterization of the charged variants with online desalting.
- Publication Part Number: 5991-5274EN
- Created: 04 Nov 2014
- 279 KB
An Agilent Bio-Monolith Protein A column determined recombinant mAb titer and was used to enrich μg amounts of antibody for further structural characterization by MS.
- Publication Part Number: 5991-5124EN
- Created: 21 Aug 2014
- 264 KB
In this application note, pre-packed Bio-monolith Protein A columns, part of the AdvanceBio family, were used to demonstrate the quick capture of monoclonal antibody titer
- Publication Part Number: 5991-2990EN
- Created: 08 Jan 2014
- 441 KB
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Workflow solutions for Optimizing Native ADC and mAb Analysis.
- Publication Part Number: 5994-2098EN
- Created: 01 June 2020
- 9 MB
A Trio of Techniques to Complete CQA Characterization.
- Publication Part Number: 5994-2097EN
- Created: 01 June 2020
- 8 MB