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Technical overview describing ion exchange method development and troubleshooting
- Publication Part Number: 5994-8708EN
- Created: 11 Nov 2025
- 466 KB
Agilent AdvanceBio spin columns to desalt fractions from oligonucleotide purification.
- Publication Part Number: 5994-8593EN
- Created: 20 Aug 2025
- 1 MB
This application note highlights excellent performance of Agilent PL-SAX columns for synthetic oligonucleotide analysis and suggests an optimal kickoff for exploring alternative method conditions.
- Publication Part Number: 5994-8381EN
- Created: 22 May 2025
- 570 KB
PLRP-S reversed-phase HPLC columns deliver the pure oligonucleotides required for genomic applications.
- Publication Part Number: 5990-8187EN
- Created: 10 Mar 2025
- 371 KB
Oligonucleotide analysis with ion-pairing-free reversed phase method and TOF LC/MS
- Publication Part Number: 5994-8013EN
- Created: 20 Dec 2024
- 587 KB
Direct 2D-LC analysis of oligonucleotides in solution with high salt content, with online desalting in the first dimension and IP-RPLC in the second dimension.
- Publication Part Number: 5991-9490EN
- Created: 14 Oct 2024
- 912 KB
This user guide describes how to calculate the amount of PL-SAX media needed to pack a column. It briefly describes best practices for loading the column.
- Publication Part Number: 5994-7818EN
- Created: 25 Sep 2024
- 217 KB
From analytical to preparative scale, Agilent AdvanceBio Oligonucleotide columns, software, and instrumentation pair seamlessly to minimize method optimization and downtime.
- Publication Part Number: 5994-6077EN
- Created: 30 June 2024
- 5 MB
AdvanceBio superficially porous columns for excellent performance and resolution for semi-prep purification of synthetic oligos without compromising column loading.
- Publication Part Number: 5994-7478EN
- Created: 31 May 2024
- 683 KB
In this application note, we explore some of the key parameters when comparing different column chemistries using ion-pair reversed-phase (IP-RP) separation of Semaglutide.
- Publication Part Number: 5994-7419EN
- Created: 08 May 2024
- 530 KB
Consumables workflow ordering guide for oligonucleotide purification using ion pair reversed-phase liquid chromatography.
- Publication Part Number: 5994-4636EN
- Created: 23 Apr 2024
- 546 KB
Easily find all you need for oligonucleotide purification using anion exchange liquid chromatography with this workflow ordering guide.
- Publication Part Number: 5994-4635EN
- Created: 22 Apr 2024
- 624 KB
Quick and efficient sample cleanup for biomolecule analysis using AdvanceBio spin cartridges and Gly-X InstantPC labeling
- Publication Part Number: 5994-7239EN
- Created: 27 Mar 2024
- 1 MB
In this application note, we explore some of the key parameters when developing an ion-pair reversed-phase (IP-RP) separation of mRNA.
- Publication Part Number: 5994-7199EN
- Created: 20 Mar 2024
- 540 KB
Molecular weight confirmation and simple characterization workflows for synthetic oligos with Agilent LC/MSD XT and MS Spectral Deconvolution feature in OpenLab CDS 2.8.
- Publication Part Number: 5994-7083EN
- Created: 28 Feb 2024
- 410 KB
Competitive comparison from analytical to semipreparative purification of synthetic oligonucleotides.
- Publication Part Number: 5994-7591EN
- Created: 26 July 2024
- 878 KB
This poster covers columns for oligonucleotide chromatography, from siRNA/ASO to mRNA.
- Publication Part Number: 5994-7567EN
- Created: 07 June 2024
- 12 MB
Agilent AdvanceBio Spin columns are designed for use with a centrifuge, and samples are ready for analysis in just 10 to 15 minutes.
- Publication Part Number: 5994-7305EN
- Created: 02 Apr 2024
- 460 KB