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Demonstion of the use of multiple heart-cutting two-dimensional liquid chromatography for automated desalting of glucagon from an MS incompatible USP method.
A guide to find the right column for your characterization workflow. It includes advice and tips on method development, solvent choice, mobile phase modification, optimization, example separations, as well as ordering information.
Presents the use of AdvanceBio Desalting-RP cartridges to pretreat mAb and ADC samples before MS analysis.
AdvanceBio Desalting - RP cartridges used for effective desalting of LC-separated monoclonal antibodies (mAbs) before characterization by mass spectrometry
Agilent Bio Mab WCX separates charged variants of papain-digest monoclonal antibody, following by MS characterization of the charged variants with online desalting.
An Agilent Bio-Monolith Protein A column determined recombinant mAb titer and was used to enrich μg amounts of antibody for further structural characterization by MS.