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This application note describes multi-attribute analysis of monoclonal antibodies using the Agilent InfinityLab 2D-LC Solution and the Agilent 6530 LC/Q-TOF system.
AdvanceBio Desalting - RP cartridges used for effective desalting of LC-separated monoclonal antibodies (mAbs) before characterization by mass spectrometry
"Fast and High Resolution Analysis of Intact and Reduced Therapeutic Monoclonal Antibodies (mAbs) using the Agilent Bio-inert LC and AdvanceBio RP-mAb Columns
Reversed-phase LC primary structure characterization workflow using Agilent AdvanceBio RP-mAb columns and Agilent 1260 Infinity Bio-Inert LC system
The charge heterogeneity provides a great challenge for the complete characterization of the monoclonal antibody (mAb).
This work describes a high flow LCMS method to demonstrate the high resolution mass analysis of mAbs with good chromatography and its utility in analysis of Biosimilar mAbs.
| Publication Part Number | 5991-4266EN | ||
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Fast and efficient LC TOF/MS characterizes intact and digested IgG to identify glycoform masses and profiles. mAb-glyco chip analysis built a glycan accurate mass database.
| Publication Part Number | 5990-2323EN | ||||
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Accurate mass intact protein analysis using 6550 iFunnel Q-TOF
| Publication Part Number | 5991-2116EN | |||
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Rapid reversed-phase separations of intact and reduced monoclonal antibodies (mAbs) were optimized using Agilent ZORBAX RRHD 300SB-C3 columns.
| Publication Part Number | 5990-9667EN | |||
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| Publication Part Number | 5990-9668EN | |||
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Application note for the fast separation of recombinant human erythropoietin Using Reversed Phased Agilent ZORBAX RRHD 300SB-C18, 1.8 μm
| Publication Part Number | 5990-9248EN | ||
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Because of the significant progress achieved in the solid phase chemical synthesis of oligonucleotides during the past four decades, synthetic oligonucleotides...